Latest News, Grants & Research Reports
Read our latest news, blog posts and research updates right here
A potential new treatment for neuroblastoma
We welcome the news that a potential new treatment for children with neuroblastoma will be advanced to clinical trial and reach more young cancer patients.
Researchers have found an indirect way to target N-Myc, a gene that occurs in aggressive forms of neuroblastoma. They found that a new drug, fadraciclib, is effective at blocking N-Myc activity by switching off the production of N-Myc and a clinical trial for children with high-risk neuroblastoma is due to open by the end of 2020.
September Research News
Read the latest neuroblastoma news from September.
New insights into neuroblastoma could help better tailor treatment for children affected by this rare and aggressive cancer.
Accelerating drug development for neuroblastoma
An international forum of leading scientists from the UK, Europe and USA, funded by national charity Neuroblastoma UK, prioritises drug development and strategies for new treatment trials for children with neuroblastoma.
In the September edition of European Journal of Cancer, Dr Lucas Moreno from Vall d’Hebron Hospital, Barcelona, and a team of international scientific and clinical experts published an agreed list of genetic targets and drugs that should be advanced for early-phase paediatric clinical trials, following the second Neuroblastoma New Drug Development Strategy (NDDS) forum.
SIOPEN High-Risk Neuroblastoma Clinical Trial 2 to open in the UK in 2021
Neuroblastoma UK with Solving Kids’ Cancer has awarded a grant of £609,762.40 to enable the SIOPEN High-Risk Neuroblastoma Clinical Trial 2 (HR-NBL2) to open in the UK. The trial is anticipated to open in early 2021.
This Phase 3 clinical trial will offer children in the UK, with a diagnosis of high-risk neuroblastoma, to have the same opportunities as children across Europe and take part in this pan-European study, enabling a series of important randomised questions to be answered within the overall framework of the trial.
Press release: Charities fund new clinical trial to help children with cancer
Neuroblastoma UK and Solving Kids Cancer have awarded a grant to enable the SIOPEN High-Risk Neuroblastoma Clinical Trial 2 (HR-NBL2) to open in the UK, it is anticipated to open in early 2021.
This Phase 3 clinical trial will offer children in the UK, with a diagnosis of high-risk neuroblastoma, to have the same opportunities as children across Europe and take part in this pan-European study.
Committed to our cause
The current and rapidly evolving situation with coronavirus presents significant challenges for the research community and every sector.
The coronavirus and government guidelines are already having a significant impact on neuroblastoma research, now and in the future. These changes, whilst temporary and very much supported by all of us at Neuroblastoma UK, may affect the pace and progress of vital neuroblastoma research.
Developing personalised treatment for children with neuroblastoma
In 2019, we awarded £236,141 to Dr Suzanne Turner at the University of Cambridge, as part our 2019 research grant round.
Here we meet Dr Turner and find out more about her three year research project aimed at improving the effectiveness of ALK inhibitors for children with neuroblastoma.
International Women's Day 2020
International Women's Day (8th March 2020) is a global day celebrating the achievements of women.
Thanks to your support, we fund amazing researchers working to improve treatments for neuroblastoma. Today we celebrate those female scientists who work tirelessly to help more children with neuroblastoma.
Can a keto diet enhance therapy for neuroblastoma?
In 2019, we awarded nearly £5,000 to Prof Robert Falconer and Xiaoxiao Guo at the University of Bradford.
This research grant enabled them to explore the potential for a ketogenic diet to enhance neuroblastoma therapy. Let’s find out more.
Understanding how neuroblastoma develops
With Children’s Cancer and Leukaemia Group (CCLG), we awarded £72,656 to Dr Anestis Tsakiridis at the University of Sheffield.
The team are working to understand how human trunk neural crest cells become cancerous. This research could lead to further investigations to stop neuroblastoma cells from developing.
Dr Tsakiridis shares his motivations, why team work matters and tells us more about his exciting work.