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A potential new treatment for neuroblastoma
We welcome the news that a potential new treatment for children with neuroblastoma will be advanced to clinical trial and reach more young cancer patients.
Researchers have found an indirect way to target N-Myc, a gene that occurs in aggressive forms of neuroblastoma. They found that a new drug, fadraciclib, is effective at blocking N-Myc activity by switching off the production of N-Myc and a clinical trial for children with high-risk neuroblastoma is due to open by the end of 2020.
Accelerating drug development for neuroblastoma
An international forum of leading scientists from the UK, Europe and USA, funded by national charity Neuroblastoma UK, prioritises drug development and strategies for new treatment trials for children with neuroblastoma.
In the September edition of European Journal of Cancer, Dr Lucas Moreno from Vall d’Hebron Hospital, Barcelona, and a team of international scientific and clinical experts published an agreed list of genetic targets and drugs that should be advanced for early-phase paediatric clinical trials, following the second Neuroblastoma New Drug Development Strategy (NDDS) forum.